[Expert Solution]: 249, A 71-year-old man comes to the office…

249, A 71-year-old man comes to the office for evaluation of dementia, He describes short term memory loss (repeating questions, forgetting to do things), he gets lost easily, and he has recent difficulty operating the television channel changer or lawn mower, The only other symptoms he describes are mild social withdrawal and occasional crying spells. The changes have progressed gradually over several years, but they have accelerated in the past 6 to 9 months. He has a history of well-controlled hypertension, type 1 diabetes mellitus, hypercholesterolemia, and coronary heart discase. He takes aspirin, metoprolol, insulin, and atorvastatin. He has no psychiatric history. Physical and neurologic examination is normal, with no signs of gait disorder or focal findings. General mental status examination is normal. His score on the Mini-Mental State Examination is 18 of 30; he missed 6 points on orien-ration, 3 on recall, 2 on serial sevens, and 1 on intersecting pentagons. Laboratory studies are normal. Magnetic resonance imaging of the brain shows moderate atrophy and moderate white matter change reported as consistent with