[Expert Solution]: E

E. M. is a woman in her mid-30’s who was diagnosed with an aggressive form of leukemia three years ago. She has undergone numerous chemotherapy agents and a bone-marrow transplant. Unfortunately, she continues to come out of remission. E. M. is desperate – she has two children under 10 – and is looking for any treatment that could cure her cancer. She has heard about a new clinical trial on a drug that treats her type of leukemia. She is not a candidate for the trial as she has already had a bone marrow transplant. She is looking for options. You asked her oncologist about this drug and how E. M. might get treatment. He said the drug is “investigational” and she might be a candidate for “compassionate grounds.” Provide definitions for these terms and discuss why E. M. might be given the drug.